Clinical Trials Directory

Trials / Completed

CompletedNCT02347774

Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-4)

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD: GOLDEN-4 (Glycopyrrolate for Obstructive Lung Disease Via Electronic Nebulizer

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
641 (actual)
Sponsor
Sunovion Respiratory Development Inc. · Industry
Sex
All
Age
40 Years
Healthy volunteers
Not accepted

Summary

This is a trial of 12 weeks of treatment with nebulized SUN-101 using an Investigational eFlow® Closed System (CS) nebulizer in subjects with chronic obstructive pulmonary disease (COPD) according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD 2014) guidelines.

Detailed description

This is a Phase 3, randomized, double-blind, placebo-controlled, parallel-group, multicenter, efficacy and safety trial of 12 weeks of treatment with nebulized SUN-101 using an Investigational eFlow® Closed System (CS) nebulizer in approximately 645 subjects with chronic obstructive pulmonary disease (COPD) according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD 2014) guidelines. SUN-101 or placebo will be administered twice daily as an oral inhalation using the investigational eFlow CS nebulizer.

Conditions

Interventions

TypeNameDescription
DRUGSUN-101 50 mcg BID eFlow (CS) nebulizerSUN-101 50 mcg twice daily (BID) eFlow (R) Closed System (CS) nebulizer
DRUGSUN-101 25 mcg BID eFlow (CS) nebulizerSUN-101 25 mcg BID eFlow (R) Closed System (CS) nebulizer
DRUGPlacebo eFlow (CS) nebulizerPlacebo BID eFlow (R) Closed System (CS) nebulizer

Timeline

Start date
2015-02-01
Primary completion
2015-12-01
Completion
2015-12-01
First posted
2015-01-27
Last updated
2018-03-13
Results posted
2018-03-13

Locations

45 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02347774. Inclusion in this directory is not an endorsement.