NCT02321761

Effect of Amantadine Administration on Spatial Functioning Following Traumatic Brain Injury

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Loewenstein Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Amantadine hydrochloride is one of the drugs given at rehabilitation programs to people who suffered Acquired Brain Injury in order to expedite recovery and improve functioning. A previous study examined the spatially asymmetric allocation of attention in patients with traumatic brain injury (TBI). Patients demonstrated significantly worse performance with leftward than with rightward cross-hemi field shifts of attention. This is reminiscence of neglect patients. This difference was significantly reduced during and following treatment. Our objective is to investigate whether Amantadine Hydrochloride is effective in improving allocation of spatial attention and improving function in people with Traumatic Brain Injury.

Conditions

• Traumatic Brain Injury

Interventions

Type	Name	Description
DRUG	Amantadine hydrochloride	Drug dosages: day 0-14 no drug will be given Days 15-21 100 mg Days 22-28 200 mg Days 29-42 400 mg Days 43-56 200 day 57-70 no drug will be given

Timeline

• Start date: 2014-06-01
• Primary completion: 2018-12-01
• Completion: 2018-12-01
• First posted: 2014-12-22
• Last updated: 2018-08-08

Locations

1 site across 1 country: Israel