NCT02292082

The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 111 (actual)
• Sponsor: Hospital for Special Surgery, New York · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Total knee replacement is associated with severe post-operative pain. The purpose of this study is to compare two methods of treatment for pain control following Total Knee Replacement with an accelerated physical therapy protocol to aid the achievement of rehab milestones.

Detailed description

A total of 106 patients undergoing total knee arthroplasty will be randomized into two groups: one to receive only Periarticular injections and the other periarticular injections AND adductor canal block. Patients will be asked their numeric pain scores before surgery as baseline and at 24 and 48 hours post-operation. Patients also will be asked questions from painOUT questionnaire at 24 and 48 hours. Time to reach discharge criteria based on physical therapy assessments will also be measured.

Conditions

• Osteoarthritis

Interventions

Type	Name	Description
DRUG	Bupivacaine
DRUG	Morphine
DRUG	Methylprednisolone
DRUG	Cefazolin
DRUG	Normal saline
DRUG	Midazolam
DRUG	Propofol
DRUG	Dexamethasone
DEVICE	8 MHz. Chiba needle, 22 G / 4 inches

Timeline

• Start date: 2014-11-01
• Primary completion: 2016-08-01
• Completion: 2016-08-01
• First posted: 2014-11-17
• Last updated: 2019-01-11
• Results posted: 2019-01-11

Locations

1 site across 1 country: United States