NCT02288715

Relationship of Cerebral Perfusion Pressure Variability to Sepsis-associated Encephalopathy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: Kang Yan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to evaluate whether variability of CPP (cerebral perfusion pressure) is related to sepsis-associated encephalopathy and outcomes of patients with sepsis.

Detailed description

Encephalopathy is a common complication of sepsis, impaired cerebrovascular autoregulation (AR) in patients with sepsis is considered related to Sepsis-associated encephalopathy (SAE). As AR is important in stabilizing the cerebral perfusion pressure, whether greater variability of CPP is related to SAE and mortality or not remains unclear. We conduct this study to evaluate the relationship between them.

Conditions

• Sepsis

Interventions

Type	Name	Description
OTHER	no interventions

Timeline

• Start date: 2014-05-01
• Primary completion: 2015-03-01
• Completion: 2017-03-01
• First posted: 2014-11-11
• Last updated: 2017-11-06

Locations

1 site across 1 country: China