NCT02287077

Umbilical Cord Milking for Neonates With Hypoxic Ischemic Encephalopathy

A Randomized Controlled Trial of Umbilical Cord Milking for Neonates With Hypoxic Ischemic Encephalopathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 101 (actual)
• Sponsor: Thomas Jefferson University · Academic / Other
• Sex: All
• Age: 1 Minute
• Healthy volunteers: Not accepted

Summary

The objective of this pilot study is to investigate the feasibility of performing umbilical cord milking in neonates who are depressed at birth.

Detailed description

Hypoxic-ischemic encephalopathy (HIE) is a brain injury in neonates due to inadequate blood flow and oxygen delivery to the neonatal brain. Umbilical cord milking can potentially improve brain injury in neonates with HIE. The objective of this study is to investigate the feasibility of performing umbilical cord milking in neonates who are depressed at birth. The investigators hypothesized that umbilical cord milking is feasible and safe in neonates who are depressed at birth. The investigators also hypothesized that umbilical cord milking will increase stem cells in neonatal blood circulation and improve short term outcomes in neonates with moderate and severe HIE.

Conditions

• Hypoxic Ischemic Encephalopathy
• Umbilical Cord Milking

Interventions

Type	Name	Description
PROCEDURE	Umbilical Cord Milking	At birth, neonate will be held below the level of placenta and umbilical cord will be milked 3 times before clamping the cord.

Timeline

• Start date: 2014-12-01
• Primary completion: 2016-10-01
• Completion: 2016-10-01
• First posted: 2014-11-10
• Last updated: 2017-12-18

Locations

1 site across 1 country: India