NCT02284178

Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 513 (actual)
• Sponsor: University of Central Florida · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Insertion of a breathing tube to enable treatment with mechanical ventilation (respirator) is often associated with complications, such as infection and lung injury. Leakage of secretions around the breathing tube (microaspiration) is a major factor leading to complications. The investigators propose that a standardized, enhanced oral suction protocol will be effective in reducing microaspiration and harms associated with mechanical ventilation. The investigators hypothesize that those randomized to the enhanced oral suction protocol will have less microaspiration and other ventilator-associated conditions than those in the usual care, standard suction group.

Conditions

• Respiratory Failure

Interventions

Type	Name	Description
OTHER	Enhanced oropharyngeal suction	Deep oropharyngeal suction with catheter every 4 hours
OTHER	Usual Care	Oral suction with suction swab every 4 hours

Timeline

• Start date: 2014-08-01
• Primary completion: 2017-08-01
• Completion: 2017-12-01
• First posted: 2014-11-05
• Last updated: 2019-08-15
• Results posted: 2019-08-15

Locations

1 site across 1 country: United States