NCT02283736

Efficacy of Oral Probiotic Administration in Patients With Chronic Periodontitis

Efficacy of Oral Probiotic Administration in Clinical, Immunological and Microbiological Parameters of Patients With Chronic Periodontitis Treated With Non Surgical Periodontal Treatment.

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Jorge Gamonal · Academic / Other
• Sex: All
• Age: 35 Years
• Healthy volunteers: Not accepted

Summary

The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic tablets as an adjunct to scaling and root planning (SRP). Material and methods: Thirty six chronic periodontitis patients will be recruited and monitored clinically, immunologically and microbiologically at baseline, 3 and 6 months after therapy. All patients will receive scaling and root planning and randomly will be assigned over an experimental (SRP + probiotic, n=18) or control (SRP + placebo, n=18) group. The tablets will be used once per day during 3 months.

Conditions

• -Chronic Periodontitis

Interventions

Type	Name	Description
OTHER	Lactobacillus rhamnosus SP1	Tablet containing Lactobacillus rhamnosus SP1
OTHER	Talc powder	Tablet containing talc powder
PROCEDURE	Periodontal treatment	Scaling and root planning

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-06-01
• Completion: 2016-12-01
• First posted: 2014-11-05
• Last updated: 2016-06-15

Locations

1 site across 1 country: Chile