Clinical Trials Directory

Trials / Completed

CompletedNCT02279953

Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder

An Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled Study on the Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
151 (actual)
Sponsor
H. Lundbeck A/S · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

To assess the efficacy of vortioxetine (10 to 20 mg/day) as adjunctive treatment to stable selective serotonin reuptake inhibitor (SSRI) dose versus stable SSRI monotherapy on cognitive performance (focusing on the aspect concerning speed of processing, executive functioning and attention) in patients who are in partial or full remission from their Major Depressive Episode (MDE).

Conditions

Interventions

TypeNameDescription
DRUGVortioxetine 10-20 mg
DRUGPlacebo
DRUGSSRIescitalopram, citalopram or sertraline

Timeline

Start date
2014-10-01
Primary completion
2016-04-01
Completion
2016-04-01
First posted
2014-10-31
Last updated
2017-05-24

Locations

17 sites across 5 countries: Estonia, Finland, Germany, Serbia, Slovakia

Source: ClinicalTrials.gov record NCT02279953. Inclusion in this directory is not an endorsement.