NCT02277977

Evaluation of Impaired Microcirculation During Septic Shock With Contrast Enhanced Ultrasound

Messung Von Mikrozirkulationsstörungen im Septischen Schock Mit Kontrastmittel- verstärkter Sonographie Evaluation of Impaired Microcirculation During Septic Shock With Contrast Enhanced Ultrasound

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University Hospital Freiburg · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Microcirculatory disorders play a central role in the pathogenesis of sepsis and septic shock. Without adequate therapy that may lead to multi-organ failure and death. Therefore useful therapeutic measures aim to improve the microcirculation, to avoid tissue hypoxia and thus multiple organ failure or death. Clinically, the microcirculation can currently be indirectly evaluated using the diuresis and metabolic parameters (eg, lactate). The aim of the present study is to measure the microcirculation in septic shock by means of contrast-enhanced sonography of the calf muscles. For this purpose, the method is applied to 24 subjects during and after septic shock. It will be investigated in this study whether the microcirculation measurement with ultrasound contrast reflects the severity of the disease. As well as to evaluate whether the use of this diagnostic method could lead to better treatment of the septic shock.

Conditions

• Sepsis

Interventions

Type	Name	Description
OTHER	Contrast enhanced ultrasound	Contrat enhanced ultrasound during septic shock

Timeline

• Start date: 2014-11-01
• Primary completion: 2015-11-01
• Completion: 2015-12-01
• First posted: 2014-10-29
• Last updated: 2022-09-02