NCT02267057

Efficacy of Pain Treatment on Depression in Patients With Dementia

Efficacy of Pain Treatment on Depression in Patients With Dementia. A Randomized Clinical Trial.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 163 (actual)
• Sponsor: University of Bergen · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether pain treatment can reduce symptoms of depression in patients suffering from dementia and depression. Depression is commonly diagnosed in patients with dementia. If the investigators find a reduction in depressive symptoms when pain treatment is applied, this will support the hypothesis that undiagnosed pain may present itself as depression in patients with dementia.

Conditions

• Depression
• Pain
• Dementia

Interventions

Type	Name	Description
DRUG	Paracetamol	Paracetamol granulate supplied by Weifa (Paracet) and 1 g paracetamol tablets produced by Kragerø tablettproduksjon for blinding purposes.
DRUG	Buprenorphine	Buprenorphine 5 micrograms/hour and 10 micrograms/hour transdermal system produced by Mundipharma, identical to placebo transdermal system.
DRUG	Paracetamol placebo	Paracetamol placebo tablets produced by Kragerø tablettproduksjon.
DRUG	Buprenorphine placebo	Buprenorphine transdermal system placebo produced by Mundipharma.

Timeline

• Start date: 2014-08-01
• Primary completion: 2016-12-21
• Completion: 2016-12-21
• First posted: 2014-10-17
• Last updated: 2017-04-04

Locations

1 site across 1 country: Norway