NCT02261987

Resistive Inspiratory Manoeuvre as Airway Clearance Technique in Cystic Fibrosis

Role of Resistive Inspiratory Manoeuvres During Bronchial Drainage Session in Cystic Fibrosis: a Randomized Crossover Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Universidad San Jorge · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

This trial aims to analyze whether the resistive inspiratory manoeuvre (RIM) performed previously to autogenic drainage (AD) technique improves the effectiveness in terms of mucus clearance during a typical bronchial drainage session in adults, stable CF patients.

Detailed description

It is a multicenter study. 4 different Spain Cystic Fibrosis Foundations are included in the study (Madrid, Valencia, Murcia and Aragón). All patients will perform three different arms of treatment in a crossover randomization. Each arm of treatment will be apply only in one session. The wash-out period will be one week. Before starting the trial, all patients will perform a control session without any intervention, only the outcome measures will be assess. During the study period the patients' pharmacological treatment remained unchanged

Conditions

• Cystic Fibrosis

Interventions

Type	Name	Description
OTHER	Autogenic drainage (AD)	It will be apply in one only session. The time spent during this bronchial drainage session will be 30 minutes All patients will perform all interventions in a randomized order.
OTHER	Resistive inspiratory manoeuvre (RIM)	It will be apply in one only session. The time spent during this bronchial drainage session will be 30 minutes All patients will perform all interventions in a randomized order.
OTHER	Resistive inspiratory manoeuvre+autogenic drainage	It will be apply in one only session. The time spent during this bronchial drainage session will be 30 minutes All patients will perform all interventions in a randomized order.

Timeline

• Start date: 2014-11-01
• Primary completion: 2016-05-01
• Completion: 2016-06-01
• First posted: 2014-10-10
• Last updated: 2016-11-15

Locations

4 sites across 1 country: Spain