Clinical Trials Directory

Trials / Terminated

TerminatedNCT02247479

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Efficacy and Safety of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
906 (actual)
Sponsor
Hoffmann-La Roche · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Conditions

Interventions

TypeNameDescription
DRUGLampalizumabParticipants will receive 10 mg dose of lampalizumab administered intravitreally.
OTHERShamA sham injection is a procedure that mimics an intravitreal injection of lampalizumab.

Timeline

Start date
2014-09-18
Primary completion
2018-01-29
Completion
2018-01-29
First posted
2014-09-25
Last updated
2019-06-26
Results posted
2019-04-23

Locations

145 sites across 19 countries: United States, Argentina, Australia, Austria, Belgium, Canada, Denmark, France, Germany, Hungary, Italy, Mexico, Netherlands, Peru, Poland, Slovakia, Spain, Switzerland, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT02247479. Inclusion in this directory is not an endorsement.