NCT02244853

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Association of Heart Rate With Cardiovascular Disease Prognosis of Patients With Stable Coronary Artery Disease: A CALIBER Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 51,703 (actual)
• Sponsor: University College, London · Academic / Other
• Sex: —
• Age: —
• Healthy volunteers: Accepted

Summary

The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study. CALIBER links patient records from four different data sources: Clinical Practice Research Database (CPRD), MINAP (Myocardial Ischaemia National Audit Project registry) Hospital Episodes Statistics (HES), the Office for National Statistics (ONS).

Detailed description

This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching aim of CALIBER is to better understand the aetiology and prognosis of specific coronary phenotypes across a range of causal domains, particularly where electronic records provide a contribution beyond traditional studies. CALIBER has received both Ethics approval (ref 09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).

Conditions

• Stable Angina
• Myocardial Infarction
• Coronary Heart Disease
• Heart Failure
• Stroke
• Death, Sudden, Cardiac
• Peripheral Arterial Disease
• Atrial Fibrillation
• Bleeding

Timeline

• Start date: 2013-09-01
• Primary completion: 2013-12-01
• Completion: 2014-12-01
• First posted: 2014-09-19
• Last updated: 2014-09-19

Locations

1 site across 1 country: United Kingdom