Trials / Completed
CompletedNCT02233647
Phendimetrazine and Cocaine
Safety and Tolerability of Cocaine During Phendimetrazine Maintenance
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 11 (actual)
- Sponsor
- William Stoops · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cocaine | The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and phendimetrazine. |
| DRUG | Placebo | The pharmacodynamic effects of placebo will be determined during maintenance on placebo and phendimetrazine. |
Timeline
- Start date
- 2014-09-01
- Primary completion
- 2015-12-01
- Completion
- 2015-12-01
- First posted
- 2014-09-08
- Last updated
- 2017-09-27
- Results posted
- 2016-09-15
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02233647. Inclusion in this directory is not an endorsement.