NCT02185443

Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases

Stereotactic Body Radiation Therapy for the Treatment of Unresectable Liver Metastases in Patients With Colorectal Adenocarcinoma, Carcinoma of the Anal Canal and Gastrointestinal Neuroendocrine Tumors

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 43 (estimated)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a Phase II study to determine the efficacy of SBRT to treat liver metastases in patients with Colorectal Adenocarcinoma, Carcinoma of the Anal Canal and Gastrointestinal Neuroendocrine Tumors that are not amenable to surgery. Patients should have no evidence of extra-hepatic disease or have disease that is planned to be treated with curative intent. Therefore, SBRT is being considered as a potentially curative procedure.

Conditions

• Liver Metastases
• Colorectal Cancer
• Anal Canal Cancer
• Gastrointestinal Neuroendocrine Tumors

Interventions

Type	Name	Description
RADIATION	SBRT	* 60Gy in 3 fractions (20Gy/fraction) over 14 days * 60Gy in 5 fractions (12Gy/fraction) over 18 days if organ at risk constraints cannot be met with fractionation above

Timeline

• Start date: 2014-05-01
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2014-07-09
• Last updated: 2024-12-09

Locations

1 site across 1 country: Brazil