Trials / Unknown
UnknownNCT02169388
Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy
Effects of Gut Microflora on the Immune and Nutritional Status of CRC Patients After Chemotherapy
- Status
- Unknown
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Shandong University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Probiotics modulate the gut microflora and immune status in CRC,which can reduce the side effects of chemotherapy such as diarrhea,infection,neutropenia etc.
Detailed description
Chemotherapy destroys the intestinal mucosal barrier, affects intestinal flora, causing bacterial translocation, infection and other complications; Probiotics may restore the intestinal immunity, mucosal barrier, and nutrient absorption.The adverse effects of chemotherapy and the malnutrition status may be relieved via probiotic administration.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Probiotic | Microbial composition using probiotic |
| DRUG | placebo（for probiotic） | microbiota modulation using placebo |
Timeline
- Start date
- 2014-06-01
- Primary completion
- 2014-10-01
- Completion
- 2015-01-01
- First posted
- 2014-06-23
- Last updated
- 2014-06-25
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02169388. Inclusion in this directory is not an endorsement.