NCT02168634

The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Kaohsiung Veterans General Hospital. · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Hypertrophic scar, a disfiguring tissue reaction to trauma, occurred in around 20 % of the population. The patients with hypertrophic scar usually seek medical assistance not just for the annoying appearance but mostly due to the intractable itchiness. There have been a variety of effective methods to alter the appearance of the scar. However, the treatments for itching from hypertrophic scar are scarce. In 2009, P.Gazerani used Botox to treat histamine-induced itch with favorable results. In the clinical setting, however, the efficacy of Botox to treat itch from hypertrophic scar was yet to be proven. Therefore, the goal of this study is to conduct a randomized controlled trials about using Botox to treat itch from hypertrophic scar.

Conditions

• Itchiness
• Hypertrophic Scar
• Botulinum Toxin

Interventions

Type	Name	Description
DRUG	Botulinum Toxins	5U botulinum toxin in 1c.c. normal saline, local injection
DRUG	Placebo	1cc normal saline, local injection

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-12-01
• First posted: 2014-06-20
• Last updated: 2015-10-09

Locations

1 site across 1 country: Taiwan