| Recruiting | Cost-Effectiveness of ESWT Plus Rehabilitation vs Rehabilitation Alone in Post-Burn Scars NCT06913257 | Al Hayah University In Cairo | N/A |
| Recruiting | Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Ge NCT07147166 | University of California, San Francisco | N/A |
| Not Yet Recruiting | Pulsed High Intensity Laser Versus Extracorporeal Shockwave Therapy on Hypertrophic Scar Post Burn NCT06803472 | Cairo University | N/A |
| Recruiting | Differential Pressure Distribution Orthosis by 3D Printing Process in the Treatment of Post-burn Hypertrophic NCT06487910 | Centre Hospitalier Régional Metz-Thionville | N/A |
| Active Not Recruiting | An Innovative Image-Based Method for Extensibility Assessment NCT06940999 | Cairo University | N/A |
| Withdrawn | Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars NCT05259137 | Nova Scotia Health Authority | Phase 2 / Phase 3 |
| Unknown | Effectiveness of Dry Needling in Linear Scar Tissue NCT06033430 | Iran University of Medical Sciences | N/A |
| Completed | COMPARISON STUY OF KINESIOTAPE AND LOW-LEVEL LASER THERAPY ON HYPERTROPHIC SCAR NCT07209891 | Cairo University | N/A |
| Unknown | Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrop NCT05196373 | Sirnaomics | Phase 1 / Phase 2 |
| Completed | Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticostero NCT07263100 | Somdech Phra Nangchao Sirikit Hospital | N/A |
| Unknown | Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic Scar NCT05771623 | Cairo University | N/A |
| Unknown | Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases NCT05488860 | Xiangya Hospital of Central South University | N/A |
| Unknown | A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar NCT05434897 | Shanghai Ark Biopharmaceutical Co., Ltd. | Phase 1 / Phase 2 |
| Active Not Recruiting | Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization NCT05478551 | Henry Ford Health System | Phase 2 / Phase 3 |
| Completed | Effect of Nd-YAG Laser on Hypertrophic Scar NCT06347081 | Cairo University | N/A |
| Completed | Class I Medical Device on Post-surgical Scars NCT05412745 | University of Rome Tor Vergata | N/A |
| Recruiting | Zinc Oxide Versus Petrolatum Following Skin Surgery NCT03561376 | Melissa Pugliano-Mauro | EARLY_Phase 1 |
| Completed | Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Sur NCT04877756 | Olix Pharmaceuticals, Inc. | Phase 2 |
| Unknown | Regenerative Effects of Human Stem Cell Media After Laser Therapy in Hypertrophic Scar NCT05004779 | Hangang Sacred Heart Hospital | N/A |
| Unknown | Comparison of Cosmetic and Functional Outcome of Silicone Sheeting and Micro-needling on Hypertrophic Scars NCT05108272 | Foundation University Islamabad | N/A |
| Recruiting | Silicone Taping for the Improvement of Abdominal Donor Site Scars NCT04506255 | Nova Scotia Health Authority | N/A |
| Unknown | Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Sca NCT04593706 | Tel-Aviv Sourasky Medical Center | N/A |
| Terminated | Use of Autologous Platelet-Rich Plasma to Treat Hypertrophic Burn Scars NCT03935594 | Vanderbilt University Medical Center | Phase 2 |
| Withdrawn | Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser NCT04364217 | Massachusetts General Hospital | N/A |
| Unknown | Comparison and Clinical Utility of the Portable Pressure Measuring Device for Garment Pressure Measurement on NCT04456543 | Hangang Sacred Heart Hospital | N/A |
| Completed | SMART Dressing for Hypertrophic Scar Treatment Post-Total Knee/Hip Arthroplasty NCT03849274 | Chinese University of Hong Kong | EARLY_Phase 1 |
| Unknown | Clinical Investigation to Evaluate the Performance of Hyaluronic Acid for the Treatment of Hypertrophic Scars NCT04614415 | Fidia Farmaceutici s.p.a. | N/A |
| Unknown | Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2. NCT04186273 | University of British Columbia | Phase 2 |
| Terminated | the Hypertrophic Scar Prevention of BMT101. NCT04012099 | Hugel | Phase 2 |
| Completed | The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar NCT03887377 | Henry Ford Health System | Phase 2 / Phase 3 |
| Completed | The Vascularity Changes of Scars With Laser Therapy NCT03986346 | The Hong Kong Polytechnic University | N/A |
| Completed | Characterization of Dyschromic Hypertrophic Scar NCT04619589 | Medstar Health Research Institute | — |
| Completed | Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar NCT03692273 | Massachusetts General Hospital | N/A |
| Completed | Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention NCT03795116 | State University of New York - Downstate Medical Center | Phase 2 |
| Unknown | Nanofat on Wound Healing and Scar Formation NCT03850119 | Universitair Ziekenhuis Brussel | N/A |
| Completed | "A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities" NCT04169490 | The Center for Clinical and Cosmetic Research | N/A |
| Completed | Pain Outcomes Following Intralesional Corticosteroid Injections NCT03630198 | Vanderbilt University Medical Center | Phase 4 |
| Unknown | Treatment of Hypertrophic Scars With Intradermal Botox NCT03631368 | Roy G. Geronemus, M.D. | Phase 2 |
| Unknown | Botulinum Toxins Intralesional Injection for Scar Pain NCT03982862 | Kaohsiung Medical University | Phase 4 |
| Unknown | Scar Tissue Analysis After Intraoperative Application of Stromal Vascular Fraction Cells Into Suture Line NCT04238468 | Katarina Zivec | N/A |
| Terminated | Hypertrophic Scar Prevention by Novel Topical Gel Application NCT03403621 | Mayo Clinic | Phase 1 / Phase 2 |
| Completed | Effects of Pulsed Dye and CO2 Laser in Treatment of Hypertrophic Burn Scars. NCT04769089 | The Metis Foundation | N/A |
| Completed | Study to Investigate the Pharmacokinetics, Safety, and Tolerability of BMT101 in Healthy Male Volunteers NCT03133130 | Hugel | Phase 1 |
| Completed | Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars NCT03777891 | Cairo University | Phase 4 |
| Completed | A Randomized Study to Evaluate the Safety and Efficacy of Various Doses of STP705 in Subjects With Hypertrophi NCT02956317 | Sirnaomics | Phase 1 / Phase 2 |
| Completed | Silicone vs Pirfenidone in the Treatment of Hypertrophic Scars and Keloids NCT06909812 | Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C. | Phase 3 |
| Completed | Effect of Elastic Bandage With Tension on the Inflammatory Response of Hypertrophic Scars NCT04643223 | Professor Fernando Figueira Integral Medicine Institute | N/A |
| Unknown | A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars NCT02246465 | RXi Pharmaceuticals, Corp. | Phase 2 |
| Completed | A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Scar Revision Surgery in Healthy NCT02030275 | RXi Pharmaceuticals, Corp. | Phase 2 |
| Unknown | The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial NCT02168634 | Kaohsiung Veterans General Hospital. | N/A |
| Unknown | A Substantial Equivalence Study of RD04723 and Predicate Device NCT01736969 | Oculus Innovative Sciences, Inc. | N/A |
| Completed | Role of Topical Putrescine (Fibrostat) for Prevention of Hypertrophic Scars in Mammoplasty Patients NCT03376620 | University of Manitoba | Phase 3 |
| Completed | A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treat NCT00754247 | University of Miami | Phase 4 |
| Withdrawn | Intron A for the Treatment of Hypertrophic Scar NCT00686478 | University of Alberta | Phase 3 |