NCT02164773

Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.

Addition of Magnesium Sulfate to Caudal for Prevention of Emergence Agitation in Children

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Male
• Age: 1 Year – 6 Years
• Healthy volunteers: Not accepted

Summary

Emergence agitation after sevoflurane anesthesia is still a problem needed to be solved.The aim of the study is to delineate the effect of caudal magnesium sulfate in children undergoing lower abdominal surgery to prevent postoperative emergence agitation.

Detailed description

Emergency agitation is considered one of the postoperative complication after sevoflurane anesthesia.In the enrollment of this study,children undergoing lower abdominal surgery will be enrolled in one of two groups.BM group, receive caudal magnesium sulfate 50 mg beside the conventional bupivacaine in the caudal space in ,B group, addition of 1 ml of normal saline0.9% to bupivacine .Monitoring of the postoperative emergence agitation by different emergence agitation scores with monitoring of sedation score.Detection of expected postoperative complications as nausea and vomiting.

Conditions

• Agitation
• Pediatric Disorder

Interventions

Type	Name	Description
DRUG	Magnesium Sulfate	use of 50mg magnesium sulfate in caudal analgesia added to 1ml/kg of 0.25% of bupivacaine in children undergoing lower abdominal surgery for prevention of postoperative emergence agitation.
DRUG	0.9%normal saline	use of 1ml of 0.9%normal saline added to 1ml/kg of 0.25% of bupivacaine in the caudal block as placebo to compare with active comparator.

Timeline

• Start date: 2013-10-01
• Primary completion: 2014-07-01
• Completion: 2014-08-01
• First posted: 2014-06-17
• Last updated: 2014-06-17

Locations

1 site across 1 country: Egypt