NCT02155842

Exercise Training in Treating Diastolic Heart Failure

High Versus Moderate Intensity Endurance Exercise Training in Treating Diastolic Heart Failure

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Norwegian University of Science and Technology · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether endurance exercise of either high or moderate intensity can reverse structural and functional changes of the heart in patients with diastolic heart failure, and to investigate which type of exercise is best in terms of aerobe capacity and quality of life. The investigators expect that high intensity endurance exercise is superior to moderate intensity endurance exercise.

Detailed description

This study is a prospective randomized controlled intervention study comparing two active arms. Eligible patients are being sampled consecutively by cardiologists, and randomized to either high or moderate intensity endurance exercise. Endpoints are measured at baseline, 4 weeks and 7 months. The intervention is considered safe, and the study has been approved by the Regional Ethics Committee (REK-midt). This project has been financially supported by the Norwegian ExtraFoundation for Health and Rehabilitation through EXTRA funds.

Conditions

• Heart Failure, Diastolic
• Ventricular Dysfunction, Left

Interventions

Type	Name	Description
BEHAVIORAL	High intensity endurance exercise
BEHAVIORAL	Moderate continuous endurance exercise

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2014-06-04
• Last updated: 2016-03-30

Locations

1 site across 1 country: Norway