Trials / Completed
CompletedNCT02144376
MRI and Microbiota Analysis in Constipation
Validation of Magnetic Resonance Imaging to Characterise Gastrointestinal Physiology, Gut Luminal Content and Its Interaction With Colonic Microbiota in Patients With Chronic Constipation
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- University of Nottingham · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to test how well magnetic resonance imaging (MRI) can measure whole gut transit time in people with constipation, and how readily it can detect a change in transit time induced by taking a dietary supplement with laxative effects.The investigators expect to demonstrate that ispaghula (psyllium) accelerates movement of matter through the intestinal tract. The investigators will also assess whether a change in gut bacteria and the chemicals that they release can be detected.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Ispaghula | |
| DIETARY_SUPPLEMENT | Maltodextrin |
Timeline
- Start date
- 2014-03-01
- Primary completion
- 2015-02-01
- Completion
- 2016-06-01
- First posted
- 2014-05-22
- Last updated
- 2017-01-05
Locations
2 sites across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT02144376. Inclusion in this directory is not an endorsement.