Trials / Completed
CompletedNCT02128399
Antimicrobial Stewardship Reduces MDRO Isolates in Critically Ill Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 978 (actual)
- Sponsor
- Jianfeng Xie · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Antimicrobial exposure is known to reduce the selection for various drug-resistant organisms. Numerous studies have demonstrated the association between antimicrobial use and MDR bacteria detection. However, to the investigators knowledge, there is few data to support the concept that reducing antibiotic use actually leads to improvements in antibiotic susceptibilities. Moreover, antimicrobial stewardship was demonstrated to reduce MDRO and was strongly recommended in clinics. As the investigators know, antimicrobial overuse, which occurs commonly in China, induces a severe antibacterial resistance. China's Ministry of Health (MOH) has established a policy about the antimicrobial stewardship. To date, the investigators do not have published documentation the effects of this policy on multidrug-resistant organism (MDRO) in critically ill patients.
Conditions
Timeline
- Start date
- 2012-06-01
- Primary completion
- 2013-05-01
- Completion
- 2013-12-01
- First posted
- 2014-05-01
- Last updated
- 2014-05-01
Source: ClinicalTrials.gov record NCT02128399. Inclusion in this directory is not an endorsement.