Trials / Completed
CompletedNCT02127333
Role of Oxygen for Vascular Dysfunction
Role of Acute and Chronic Hypoxemia for Vascular Function
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 38 (actual)
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie · Academic / Other
- Sex
- Male
- Age
- 40 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
Hypoxemia may contribute increased morbidity and mortality in chronic obstructive pulmonary disease (COPD) patients. We aim to characterize the role of acute and chronic hypoxemia for vascular function. For this purpose we measure capillary oxygen concentration and vascular. Vascular function is assessed by flow-mediated dilation oft he brachial artery, forearm blood flow and laser doppler perfusion imaging. We hypothesize that hypoxemia leads to impaired vascular function.
Conditions
- Endothelial Dysfunction
- FMD
- IMT
- Microcirculation
- Oxygen Pressure
- Carbon Dioxide Pressure
- Oxygen Saturation
- Forced Expiratory Volume After 1 Second
Timeline
- Start date
- 2011-01-01
- Primary completion
- 2013-09-01
- Completion
- 2013-09-01
- First posted
- 2014-04-30
- Last updated
- 2014-12-16
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02127333. Inclusion in this directory is not an endorsement.