NCT02115230

Renal Denervation in Patients With Heart Failure With Normal LV Ejection Fraction

Transcatheter Renal Denervation in Heart Failure With Normal Left Ventricular Ejection Fraction - a Safety and Efficacy Study of Irrigated Radiofrequency Catheter

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: InCor Heart Institute · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

It is a randomized prospective controlled study of transcatheter renal denervation in patients with Heart Failure With Normal LV Ejection Fraction. The purpose of the study is to evaluate the safety and effectiveness of renal denervation in patients with Heart Failure With Normal LV Ejection Fraction, due to reduction in renal and systemic sympathetic activity.

Conditions

• Heart Failure, Diastolic
• Hypertension

Interventions

Type	Name	Description
PROCEDURE	Renal denervation + medical therapy	Renal denervation + medical therapy Renal sympathetic denervation with an irrigated radiofrequency catheter with Celsius Thermocool (Biosense Webster, California, USA) + standard optimized medical therapy for diastolic heart failure

Timeline

• Start date: 2014-04-01
• Primary completion: 2016-07-01
• First posted: 2014-04-15
• Last updated: 2014-04-15

Locations

1 site across 1 country: Brazil