NCT02103881

Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital

A Double Blinded Randomized Trial of Ketamine Versus Haloperidol for Severe Prehospital Agitation

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Hennepin Healthcare Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This research study is being done to find out if one of two drugs, ketamine or haloperidol, is better for treating agitation. Agitation is a state of extreme emotional disturbance where patients can become physically aggressive or violent, endangering themselves and those who are caring for them. Often chemical substances or severe mental illness is involved in this level of agitation. Specifically, the investigators are interested in studying agitation that is treated in the prehospital setting by paramedics. This study's hypothesis is that ketamine is superior to haloperidol for treatment of agitation in the prehospital environment.

Conditions

• Agitation

Interventions

Type	Name	Description
DRUG	Ketamine	500 mg of intramuscular ketamine for severe pre-hospital agitation
DRUG	Haloperidol	Haloperidol 10 mg intramuscular for severe prehospital agitation.

Timeline

• Start date: 2014-04-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2014-04-04
• Last updated: 2017-07-24