NCT02102360

Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This clinical study compared a conventional surgical technique (CST) and a minimally invasive surgical technique (MIST) in the regenerative treatment of mandibular furcation defects.

Detailed description

Using a split-mouth design, fifteen patients with bilateral class II and III furcation defects were treated with MIST (Test Group) or CST (Control Group). Furcation defects in both groups were filled with anorganic bovine bone (ABB) and enamel matrix derivative (EMD). Patient-centered outcomes including analyses of pain, discomfort, edema, hematoma, root hypersensitivity and daily activities interference were recorded using a Visual Analogue Scale seven days after surgeries. Clinical and radiographic parameters were assessed at baseline and 6 months postoperatively. Data were statistically analysed.

Conditions

• Furcation Defects
• Periodontal Disease

Interventions

Type	Name	Description
DEVICE	Anorganic Bovine Bone	used to improve periodontal regenerative procedures.
DEVICE	Enamel Matrix Derivative	used to improve periodontal regenerative procedures.

Timeline

• Start date: 2012-03-01
• Primary completion: 2013-11-01
• Completion: 2013-12-01
• First posted: 2014-04-02
• Last updated: 2014-04-02

Locations

1 site across 1 country: Brazil