NCT02091843

Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder

Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (estimated)
• Sponsor: VA Greater Los Angeles Healthcare System · Federal
• Sex: Male
• Age: 25 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Posttraumatic stress disorder (PTSD) affects approximately 30 % of American veterans returning from Iraq and Afghanistan. Although the current therapy is effective, a percentage of patients will fail to improve and will develop chronic treatment-resistant PTSD. Patients suffering from PTSD experience intense suffering, lack of productivity and a higher risk of suicide. Unfortunately, combat PTSD has a tendency to be resistant to current treatments. The central goal of this project is to develop a new therapeutic strategy involving the placement of intracranial electrodes to treat the symptoms of PTSD. The project is based on recent evidence showing abnormal activity in a specific brain region of PTSD patients, thought to be responsible for the core symptoms of PTSD.

Conditions

• Posttraumatic Stress Disorder

Interventions

Type	Name	Description
PROCEDURE	DBS of the Basolateral Nucleus of the Amygdala
DEVICE	Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala

Timeline

• Start date: 2014-01-01
• Primary completion: 2024-12-01
• Completion: 2025-12-31
• First posted: 2014-03-19
• Last updated: 2022-10-14

Locations

1 site across 1 country: United States