NCT02068144

The Effect of Cranberry Extract Supplementation on Cardiovascular Risk Factors in Obese, Insulin Resistant Humans

The Effect of Daily Dietary Supplementation With Cranberry Extract on Modulation of Cardiovascular Risk Factors in Obese, Insulin Resistant Human Subjects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the health benefits of cranberry extract in people who are at risk for diabetes and heart problems.

Detailed description

This study will be a double-blinded, randomized, placebo-controlled, pilot study in which subjects with pre-diabetes will be randomized to receive either placebo or Cranberry extract for a total of 8 weeks of treatment. Each subject will continue on the same dosage of cranberry extract or matching placebo for the entire duration of treatment. Comparisons for insulin sensitivity, endothelial function, and markers of inflmmation and oxidative stress will be made between the 2 groups pre and post intervention.

Conditions

• Insulin Resistance
• Atherosclerosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cranberry Extract	Participants will drink one 15.2 oz bottle of Cranberry Extract beverage daily for 8 weeks.
OTHER	Placebo	Participants will drink one 15.2oz bottle of placebo beverage daily for 8 weeks.

Timeline

• Start date: 2014-02-01
• Primary completion: 2016-06-02
• Completion: 2018-07-11
• First posted: 2014-02-21
• Last updated: 2018-08-28

Locations

1 site across 1 country: United States