NCT02066337

Effect of Ozone Gel on Treatment of Chronic Periodontitis

Effect of Ozone Gel on Alveolar Bone Density and Superoxide Dismutase in Chronic Periodontitis: A Randomized Controlled Clinical Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: October 6 University · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Accepted

Summary

To evaluate the efficacy of locally delivered ozone gel as an adjunct to conventional periodontal therapy on selected clinical parameters as well as alveolar bone density (BD) and superoxide dismutase (SOD) activity in patient with chronic periodontitis.

Detailed description

In this study, the investigators tested the effect of ozone gel as a local delivery system in treatment of chronic periodontitis in term of probing pocket depth reduction, mean gain in clinical attachment level, a more rise in BD values as well as greater reduction in SOD activity compared to scaling and root planing (SRP) alone.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
PROCEDURE	scaling and root planing
DRUG	placebo gel
DRUG	Ozonated olive oil gel

Timeline

• Start date: 2013-03-01
• Primary completion: 2014-01-01
• Completion: 2014-02-01
• First posted: 2014-02-19
• Last updated: 2014-02-20

Locations

1 site across 1 country: Egypt