NCT02014389

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Objective Perimetry in Normal Subjects,Glaucoma Patients and Retinal Dystrophy Patients

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Sheba Medical Center · Other Government
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.

Detailed description

Pupil light reflex (PLR) will be measured by a chromatic multifocal pupillometer in response to short and long wavelength light with small spot stimulus in 76 points of the 30 degree visual field. A computerized infrared video pupillometer will be used to record changes in pupil diameter in response to short- and long-wavelength stimuli (peak 485 nm and 620 nm, respectively) presented by 76 LEDs, 1.8mm spot size, at light intensities of 10-3000 cd/m2 and duration of 1-3 sec at different points of the 30 degree visual field

Conditions

• Retinal Dystrophies
• Retinitis Pigmentosa
• Glaucoma

Timeline

• Start date: 2013-12-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2013-12-18
• Last updated: 2024-04-25

Locations

1 site across 1 country: Israel