Clinical Trials Directory

Trials / Completed

CompletedNCT02014363

Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD)

Double Blind, Non-inferiority Study to Evaluate the Antidepressant Activity of ETS6103 Compared to Amitriptyline in Treating Major Depressive Disorder in Patients With Unsatisfactory Response to Selective Serotonin Re-uptake Inhibitors.

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
164 (actual)
Sponsor
e-Therapeutics PLC · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

To demonstrate that the antidepressant activity of ETS6103 is not inferior to amitriptyline in subjects who have an unsatisfactory response to / are resistant to treatment with SSRIs.

Conditions

Interventions

TypeNameDescription
DRUGETS6103 (low dose)
DRUGETS6103 (high dose)
DRUGAmitriptyline

Timeline

Start date
2013-10-01
Primary completion
2015-10-01
Completion
2015-10-01
First posted
2013-12-18
Last updated
2017-01-11
Results posted
2017-01-11

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT02014363. Inclusion in this directory is not an endorsement.