NCT01993342

Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients

Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients With Joint Pain and Effusion

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 35 (estimated)
• Sponsor: Parc Taulí Hospital Universitari · Academic / Other
• Sex: All
• Age: 50 Years – 81 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the concentration of different adipocytokine (adiponectin, leptin, resistin, visfatin, osteopontin) and an inflammation classic markers as Interleukine 1 beta, tumor necrosis alfa, interleukine 6 and high sensibility reactive c protein in the synovial fluid of knee osteoarthritis patients, and compare with the inflammation detected with ultrasonography evaluation of the joint. In last years, some studies appeared focusing on the role of adipocytokines in osteoarthritis and they correlated adipocytokines with cartilage degradation and x-ray degree; in our study we will focused in the importance of adipocytokines in the inflammatory changes more than in joint destruction.

Conditions

• Osteoarthritis

Interventions

Type	Name	Description
OTHER	arthrocentesis	The made a diagnostic arthrocentesis to all patient we included
OTHER	ultrasonography of the knee	We explored the affected knee with an ultrasound explanation in order to describe inflammatory changes based on standard examination.

Timeline

• Start date: 2013-10-01
• Primary completion: 2013-11-01
• Completion: 2014-03-01
• First posted: 2013-11-25
• Last updated: 2013-11-25

Locations

1 site across 1 country: Spain