NCT01977339

Efficacy of Single Injection Femoral Nerve Block With Liposomal Bupivacaine for Total Knee Arthroplasty

A Randomized, Double-Blinded, Control Trial to Evaluate the Efficacy of Single Injection Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia in Subjects Undergoing Unilateral Total Knee Arthroplasty

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: St. Luke's-Roosevelt Hospital Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare the quality and duration of pain relief after a total knee replacement provided by a single shot of standard bupivacaine versus a single shot of liposomal bupivacaine, at the site of the femoral nerve. It is hypothesized that the liposomal bupivacaine formulation will provide more effective pain relief than standard bupivacaine.

Conditions

• Total Knee Arthroplasty

Interventions

Type	Name	Description
DRUG	Liposome Bupivacaine	10 cc of 266 mg liposome bupivacaine with 10 cc of Normal Saline
DRUG	Bupivacaine	20 cc of 0.25% bupivacaine

Timeline

• Start date: 2015-05-01
• Primary completion: 2016-07-01
• Completion: 2016-07-01
• First posted: 2013-11-06
• Last updated: 2017-04-20

Locations

1 site across 1 country: United States