Trials / Completed
CompletedNCT01976884
Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 71 (actual)
- Sponsor
- Changhai Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Immunosuppression is the leading cause of death in septic patients. Neutrophils are classical components of innate immunology, but recent studies showed that neutrophils might display antigen presenting function and inhibit lymphocyte proliferation by expressing programmed cell death 1 ligand 1 (PD-L1). Whether neutrophils express PD-L1 and its role in immunosuppression during sepsis remain unclear.
Conditions
Timeline
- Start date
- 2011-06-01
- Primary completion
- 2013-01-01
- Completion
- 2013-01-01
- First posted
- 2013-11-06
- Last updated
- 2013-11-06
Source: ClinicalTrials.gov record NCT01976884. Inclusion in this directory is not an endorsement.