NCT01966315

The Comparison of Dexmedetomidine and Midazolam for the Sleep in Intensive Care Unit

The Comparison of Dexmedetomidine and Midazolam for the Sleep of Mechanical Ventilated Intensive Care Unit Patients

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 5 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography in critically ill patients. And the investigators also compare the incidence of delirium between the two groups.

Detailed description

Sleep is very important for cognitive and immune function. However, patients in intensive care unit (ICU) have a very poor sleep. Almost all ventilated patients in intensive care unit (ICU) take a sedative drug. In Korea, most commonly used sedative drugs are dexmedetomidine and midazolam. The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography. And the investigators also compare the incidence of delirium between the two groups.

Conditions

• Poor Quality Sleep
• Sleep Deprivation
• Sleep Arousal Disorders
• Delirium

Timeline

• Start date: 2013-10-01
• Primary completion: 2016-03-01
• Completion: 2016-12-01
• First posted: 2013-10-21
• Last updated: 2019-04-23

Locations

1 site across 1 country: South Korea