Trials / Unknown
UnknownNCT01959906
Circumferential Section Pane Less Than 1 mm in Esophagectomy for Esophageal Cancer.
Prognostic Value of a Circumferential Section Pane Less Than 1 mm in Esophagectomy for Esophageal Cancer.
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 923 (actual)
- Sponsor
- University Hospital, Gasthuisberg · Academic / Other
- Sex
- All
- Age
- 18 Years – 95 Years
- Healthy volunteers
- Not accepted
Summary
A suspicious circumferential resection margin (CRM), defined as tumor cells within 1 mm of the CRM, is still controversial. The aim of this study was to compare the clinical significance of a suspicious CRM to histologically positive (R1) and negative margin (R0) resections in patients with pT3 esophageal and GE-Junction tumors.
Detailed description
From our prospectively build database 923 consecutive pT3 patients operated between january 1990 and june 2013 were selected. CRM status in patients treated by surgery only (n = 747) or after neoadjuvant therapy (n = 176) was recorded prospectively after surgery. Kaplan-Meier survival curves were generated, and factors affecting survival were assessed by Cox regression multivariate analysis.
Conditions
Timeline
- Start date
- 2013-07-01
- Primary completion
- 2013-12-01
- Completion
- 2014-06-01
- First posted
- 2013-10-10
- Last updated
- 2013-10-10
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT01959906. Inclusion in this directory is not an endorsement.