Trials / Terminated
TerminatedNCT01956474
CXL-04 A Study of Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas
Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 1,324 (actual)
- Sponsor
- Cxlusa · Industry
- Sex
- All
- Age
- 8 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the efficacy of ultraviolet-A (UVA)-induced cross-linking of corneal collagen (CXL) as a method to increase the biomechanical and biochemical stability of the cornea by inducing additional cross-links within or between collagen fibers using UVA light and the photo- mediator riboflavin.
Detailed description
This study will evaluate the results of Corneal Collagen Crosslinking (CXL) in patients with conditions that include Keratoconus, Pellucid Marginal degeneration, Post-LASIK ectasia, and patients with radial keratotomy who experience fluctuation in their vision. This is an outcomes study, all patients receive treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Theralight crosslinking and Riboflavin | Corneal Collagen cross linking with UV light and riboflavin |
Timeline
- Start date
- 2013-01-01
- Primary completion
- 2017-02-03
- Completion
- 2017-02-03
- First posted
- 2013-10-08
- Last updated
- 2018-10-12
Locations
6 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01956474. Inclusion in this directory is not an endorsement.