NCT01955785

Respiratory Treatment of Patients With Moderate and Severe Traumatic Brain Injury

Respiratory Treatment of Patients With Moderate and Severe Traumatic Brain Injury: A Randomised Comparison of Pressure Controlled Ventilation and Pressure Regulated Volume Controlled Ventilation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Norwegian University of Science and Technology · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

Intracranial pressure (ICP) in patients with traumatic brain injury (TBI) is influenced by several factors of which one is arterial CO2 tension. Patient with TBI are often sedated and mechanically ventilated in order to secure a stable PaCO2. This study compares two ventilation modus; Pressure Controlled Ventilation (PC) and Pressure Regulated Volume Controlled ventilation (PRVC) in order to observe which of the two ventilation strategies results in a more stable ICP and arterial CO2 pressure (PaCO2).

Conditions

• Traumatic Brain Injury

Interventions

Type	Name	Description
DEVICE	pressure controlled ventilator
DEVICE	Pressure Regulated Volume Controlled Ventilator

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-09-01
• Completion: 2015-09-01
• First posted: 2013-10-08
• Last updated: 2016-07-29

Locations

1 site across 1 country: Norway