NCT01948947

Improving Functions in MTBI Patients With Headache by rTMS

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Due to recent wars in Afghanistan and Iraq, the number of Veteran suffering from Mild traumatic brain(MTBI) injury and PTSD increases rapidly. Headache is one of the most debilitating clinical symptoms in Veteran with MTBI and the cause of it is still not entirely clear. Recently, the use of non-invasive brain stimulation such as repetitive transcranial magnetic stimulation(rTMS) has yielded favorable clinical outcome in a few intractable chronic central pain conditions including headaches. This study aims to 1) assess the effect of rTMS in relieving headache and improving neurophysiological functions; and 2)explore the neuronal mechanisms associated with MTBI related headache and the analgesic effect of rTMS with function magnetic resonance imaging (fMRI).

Detailed description

This study will only be conducted at the Veterans Affair hospital in San Diego.

Conditions

• TBI (Traumatic Brain Injury)

Interventions

Type	Name	Description
DEVICE	Transcranial Magnetic Stimulation	Active-repetitive transcranial magnetic stimulation (rTMS) at the dorsal lateral prefrontal cortex.
DEVICE	Sham Transcranial Magnetic Stimulation	Sham rTMS will consist of the same parameters as active, however, the subject will be shielded from the magnetic field of the coil.

Timeline

• Start date: 2014-05-01
• Primary completion: 2016-09-01
• Completion: 2016-09-01
• First posted: 2013-09-24
• Last updated: 2018-03-26
• Results posted: 2018-03-26

Locations

1 site across 1 country: United States