| Not Yet Recruiting | Adaptation of the STAIR-NT for First Responders NCT07212140 | Florida State University | N/A |
| Not Yet Recruiting | Nanopulse Laser Therapy NCT07520383 | The University of Texas Medical Branch, Galveston | Phase 1 |
| Recruiting | Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients. NCT07319208 | Nantes University Hospital | Phase 3 |
| Not Yet Recruiting | fNIRS for Disorders of Consciousness NCT07485361 | University of California, Los Angeles | — |
| Not Yet Recruiting | Efficacy and Safety of 6Degrees MyMove Interactive Virtual Reality Compared to Passive Virtual Reality in Suba NCT07441798 | Reuth Rehabilitation Hospital | N/A |
| Withdrawn | The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 | Goddess Zena I. Jones | N/A |
| Recruiting | Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test NCT07373509 | Shawn Eagle | — |
| Not Yet Recruiting | Neuro-Inflammation in Extremity Trauma: Risk Verification in Elbow Trauma: The NERVE Study NCT07259382 | Université de Montréal | — |
| Terminated | Cervical Transcutaneous SCS for TBI NCT07147816 | Roberto de Freitas | N/A |
| Not Yet Recruiting | Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple NCT07209943 | Cognixion | N/A |
| Recruiting | Cognitive Rehabilitation for Refugees With Traumatic Brain Injury and Cognitive Impairment NCT06839079 | Massachusetts General Hospital | N/A |
| Recruiting | Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy NCT07214415 | Summit Hyperbarics and Wellness | Phase 2 |
| Not Yet Recruiting | Placing External Ventricular Drains Using Assistive Augmented Reality or Image-Based Localization NCT07042048 | The Cooper Health System | N/A |
| Recruiting | Evaluation of Decision-Making Fatigue After Traumatic Brain Injury NCT07103200 | University of Minnesota | N/A |
| Recruiting | Depth Electrode Detection of Cortical Spreading Depolarization After Traumatic Brain Injury NCT05205174 | University of Minnesota | N/A |
| Recruiting | Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury NCT06867666 | Noctem, LLC | N/A |
| Recruiting | Stimulating After Recovery From Traumatic Brain Injury NCT05327829 | University of Minnesota | EARLY_Phase 1 |
| Recruiting | Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury NCT06467708 | University of Texas Southwestern Medical Center | N/A |
| Recruiting | Mindfulness for Cognition in Early-stage Alzheimer's Disease NCT06792877 | VA Boston Healthcare System | N/A |
| Recruiting | Evaluating the Impact of Adjuvant Use of Beta Blockers on Clinical Outcomes in Patients With Traumatic Brain I NCT06836856 | Mansoura University | Phase 1 / Phase 2 |
| Recruiting | DBS for Cognitive Deficits After Traumatic Brain Injury NCT06818864 | Sunnybrook Health Sciences Centre | Phase 1 |
| Not Yet Recruiting | Acquired Brain Injury and Neurorehabilitation: the Influence of Psychological Characteristics NCT06661512 | Institut Guttmann | — |
| Recruiting | Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study NCT06024122 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Completed | Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI) NCT06037603 | University of Nevada, Las Vegas | N/A |
| Unknown | Propranolol for the Treatment of Traumatic Brain Injury NCT06262061 | London Health Sciences Centre | EARLY_Phase 1 |
| Enrolling By Invitation | Impact Of Early Cognitive Rehabilitation On Functional Outcomes Following Moderate Traumatic Brain Injury NCT06981897 | Amany Saadallah Hassan Mobarez | N/A |
| Recruiting | InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI NCT06005194 | University of Washington | N/A |
| Recruiting | Evaluation of Well-being Interventions in Adults With TBI NCT05943756 | Kessler Foundation | N/A |
| Recruiting | Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury NCT06480838 | University of Texas Southwestern Medical Center | — |
| Completed | Effect of Enteral Formula (Commercial vs. Homemade) on Muscle Mass in Trauma Brain Injury NCT06949163 | Hospital General "Dr. Miguel Silva" de Morelia | N/A |
| Completed | The Exercise and Concussion Health Study NCT06494592 | Northeastern University | N/A |
| Unknown | Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetom NCT05340803 | Assiut University | Phase 3 |
| Unknown | Clinical Significance of circMETTL9 Gene in Traumatic Brain Injury NCT05484921 | Affiliated Hospital of Nantong University | — |
| Terminated | Cooling Helmets to Decrease Concussion Symptoms NCT05473897 | Corewell Health South | N/A |
| Unknown | Dynamic Decompressive Craniotomy NCT05051488 | Rohit Khanna, MD | — |
| Recruiting | Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches NCT05176392 | Veterans Medical Research Foundation | N/A |
| Recruiting | Long Lasting Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Traumatic Brain Injury Patients NCT07430150 | Assaf-Harofeh Medical Center | — |
| Completed | Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms NCT04776304 | Walter Reed National Military Medical Center | N/A |
| Recruiting | Augmented Renal Clearance in Neurocritical Care NCT07410624 | University of Alberta | — |
| Completed | VR Cognitive Rehabiliation for Pediatric TBI NCT04526639 | University of Massachusetts, Lowell | N/A |
| Unknown | REACH Hope Intervention for Dementia and TBI Caregivers NCT04969796 | Memphis VA Medical Center | N/A |
| Unknown | Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases NCT04728438 | Xiangya Hospital of Central South University | — |
| Unknown | Concussion Assessments in Football NCT05713942 | Federation Internationale de Football Association | — |
| Recruiting | Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial NCT04565119 | University of Pennsylvania | — |
| Unknown | Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabi NCT04723745 | VA Boston Healthcare System | — |
| Active Not Recruiting | Follow-up of MTBI Patients Discharged from the ED Using Standard Clinical Triage Including BrainScope One NCT04279431 | BrainScope Company, Inc. | — |
| Unknown | Cognitive Support Technology for Postsecondary Students With Traumatic Brain Injuries NCT05054855 | Kent State University | N/A |
| Recruiting | Cognitive Remediation in Forensic Mental Health Care NCT04610697 | The Royal Ottawa Mental Health Centre | N/A |
| Completed | Evaluation of the Effect of Neuroprotective Drug on Treatment Result in Patients After Traumatic Brain Injury NCT05807503 | Pomeranian Medical University Szczecin | — |
| Recruiting | Growth Hormone Replacement Therapy for Retried Professional Football Players NCT04121780 | Center for Neurological Studies | Phase 2 |
| Completed | Pediatric Guideline Adherence and Outcomes- Argentina NCT03896789 | University of Washington | N/A |
| Completed | Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbar NCT04095377 | QuantalX Neuroscience | — |
| Unknown | Electrical Stimulation in Traumatic Brain Injury (TBI) Induced Aphasia NCT03882502 | University Medicine Greifswald | N/A |
| Unknown | Validation of an Ecological Organization and Problem Solving Test (TEM-PRO) in Vocational Rehabilitation NCT04087486 | Clinique Romande de Readaptation | — |
| Unknown | Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1) NCT06195345 | Children's Hospital Los Angeles | — |
| Completed | Studying Trends of Auto-Regulation in Severe Head Injury in Paediatrics NCT05688462 | Shruti Agrawal | — |
| Unknown | MR Imaging Study of TBI in Children NCT03034031 | Sheba Medical Center | — |
| Unknown | The Effects of MBSR on Patients With TBI and Chronic Insomnia NCT03560843 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Completed | Self-Advocacy for Independent Life (SAIL) After TBI NCT03385824 | Craig Hospital | N/A |
| Completed | The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol NCT04034771 | Cairo University | Phase 3 |
| Completed | Brain Markers of Improvements in Cognitive Functioning NCT03490110 | VA Office of Research and Development | N/A |
| Completed | Guided Training for People With Cognitive Impairment NCT03225768 | Taipei Medical University WanFang Hospital | N/A |
| Terminated | Improving Functional Ability in Chronic TBI With Intensive Rehabilitation Robotic Gait Training NCT03438409 | Indiana University | N/A |
| Completed | Deep Brain Stimulation for the Treatment of Traumatic Brain Injury NCT02881151 | Jaimie M. Henderson | N/A |
| Withdrawn | Timing of VTE Prophylaxis in TBI NCT03081169 | Loyola University | Phase 4 |
| Completed | Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment NCT03265912 | ElMindA Ltd | — |
| Active Not Recruiting | Autologous Stem Cell Study for Adult TBI (Phase 2b) NCT02525432 | The University of Texas Health Science Center, Houston | Phase 2 |
| Terminated | Effects of an Interdisciplinary Fitness and Social Engagement Intervention NCT03160313 | Washington D.C. Veterans Affairs Medical Center | N/A |
| Completed | Brain Aging in Veterans (BRAVE) Training: A Cognitive Training Pilot Trial in Older Veterans With Traumatic Br NCT02561403 | San Francisco Veterans Affairs Medical Center | N/A |
| Unknown | Asia Coma Electrical Stimulation (the ACES Trial) NCT02645578 | RenJi Hospital | Phase 3 |
| Completed | Frontoparietal Priority Maps as Biomarkers for MTBI NCT02251002 | University of Minnesota | — |
| Completed | Fast MR for Young Children With Traumatic Brain Injury NCT02392975 | University of Colorado, Denver | N/A |
| Completed | Digital Gaming for Persons With Traumatic Brain Injury NCT02425527 | University of Turku | N/A |
| Completed | ESWT as a Treatment for Chronic NHO in TBI Patients NCT02331628 | Loewenstein Hospital | N/A |
| Completed | Improving Functions in MTBI Patients With Headache by rTMS NCT01948947 | VA Office of Research and Development | N/A |
| Completed | Traumatic Brain Injury in Veterans and Near-Infrared Phototherapy NCT02635516 | Cerehealth Corp. | N/A |
| Unknown | The Development of a Virtual Reality Program to Improve Attention in Individuals With TBI NCT03605017 | Kessler Foundation | N/A |
| Completed | Evaluation of Military Service and Family Members for Post Concussive and Posttraumatic Stress Symptoms NCT03191357 | Uniformed Services University of the Health Sciences | — |
| Completed | Concussion in Motor Vehicle Accidents: The Concussion Identification Index NCT02858544 | Clionsky Neuro Systems Inc. | — |
| Completed | Simvastatin for mTBI NCT01952288 | VA Office of Research and Development | Phase 4 |
| Completed | Traumatic Brain Injury and Risk for Chronic Traumatic Encephalopathy NCT02003183 | University of California, Los Angeles | — |
| Completed | Study of Cerebral Tissue Oxygenation During Transfusion in Traumatic Brain Injury NCT01728831 | Unity Health Toronto | — |
| Completed | Effectiveness of Multimodal Cognitive Rehabilitation for Traumatic Brain Injury Sustained During Older Adultho NCT04590911 | Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal | N/A |
| Completed | The EPIC Project: Impact of Implementing the EMS Traumatic Brain Injury Treatment Guidelines NCT01339702 | University of Arizona | — |
| Completed | Top-Down Executive Control in Traumatic Brain Injury (TBI), PTSD and Combined NCT01072006 | VA Office of Research and Development | — |
| Completed | The Multicenter Italian INCEPT (INfarto CErebrale Post-Traumatico) Study NCT02430324 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | — |
| Completed | Hyperbaric Oxygen Therapy (HBOT) in Chronic Traumatic Brain Injury (TBI)/Post Concussion Syndrome (PCS) and TB NCT00760734 | Paul G. Harch, M.D. | Phase 1 |
| Active Not Recruiting | Cognitive Profile of Patients at the Sagol Center for Hyperbaric Medicine and Research NCT04287283 | Assaf-Harofeh Medical Center | — |
| Completed | A Multi-Center Study of Near-Infrared Spectroscopy (NIRS) for Hematoma Detection NCT00576147 | InfraScan, Inc. | N/A |
| Completed | Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI NCT00409058 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Pharmacological Intervention in Depression After Traumatic Brain Injury NCT00205491 | Virginia Commonwealth University | Phase 4 |
| Completed | Dynamic and Static Autoregulation After Brain Injury NCT01069250 | Johannes Gutenberg University Mainz | — |