NCT01914211

The Role of Tranexamic Acid in Reducing Blood Transfusion Requirements After Cardiopulmonary Bypass in Neonates

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: Aymen N Naguib · Academic / Other
• Sex: All
• Age: 28 Days
• Healthy volunteers: Not accepted

Summary

This is an observational, prospective study to evaluate the role of tranexamic acid in reducing blood transfusion in neonates undergoing cardiopulmonary bypass.

Conditions

• Congenital Heart Disease

Interventions

Type	Name	Description
DRUG	Tranexamic Acid	100mg/kg prior to incision, 100mg/kg on CPB and 100mg/kg after reversal of heparin with protamine.
PROCEDURE	Acute Normovolemic Hemodilution	Draw 20 mL/kg (up to 5Kg) of blood from patient and replace with washed PRBCs at 10-20mL/kg. (If \> 5Kg draw 20% of circulating blood volume without PRBC replacement)

Timeline

• Start date: 2013-07-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2013-08-02
• Last updated: 2017-02-01

Locations

1 site across 1 country: United States