Clinical Trials Directory

Trials / Terminated

TerminatedNCT01908803

Proof-of-Concept Study of a Single Application of an Investigational Otic Suspension in Treatment of Acute Otitis Media With Tympanostomy Tubes

Proof of Concept of Single Application of AL-60371/AL-817 Otic Suspension in Treatment of Acute Otitis Media With Tympanostomy Tubes Compared to CIPRODEX® (BID for 7 Days)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
84 (actual)
Sponsor
Alcon Research · Industry
Sex
All
Age
6 Months – 12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate a single application of AL-60371/AL-817 Otic Suspension relative to ototopical CIPRODEX for sustained clinical cure, microbiological success, and time to cessation of otorrhea.

Detailed description

The results at the time of the interim analysis met the futility criteria and the study was subsequently stopped.

Conditions

Interventions

TypeNameDescription
DRUGAL-60371/AL-817 otic suspension
DRUGCiprofloxacin 0.3%/dexamethasone 0.1% otic suspensionCIPRODEX®

Timeline

Start date
2013-12-01
Primary completion
2014-08-01
Completion
2014-08-01
First posted
2013-07-26
Last updated
2017-12-06
Results posted
2015-09-24

Source: ClinicalTrials.gov record NCT01908803. Inclusion in this directory is not an endorsement.