Trials / Unknown
UnknownNCT01906918
Application of Remote Ischemic Preconditioning in Patients Undergoing Open Heart Surgeries
Evaluation of Remote Preconditioning on Heart Resistance to Ischemia and Reperfusion Injury
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- Sponsor
- University of Campinas, Brazil · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Strategies for myocardial protection during open heart surgeries are desired. Several experimental studies have shown beneficial effects of remote ischemic preconditioning (RIPC). The underlying mechanisms are not totally understood. This study intends to evaluate molecular mechanisms involved with RIPC on myocardium of patients underwent open heart surgeries.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | IRPC, Remote preconditioning | The patients will be submitted to 5 minutes of upper limb compression by cuff followed by 5 minutes of reperfusion. This cycle will be repeated 4 times. |
Timeline
- Start date
- 2013-08-01
- Primary completion
- 2015-08-01
- Completion
- 2015-08-01
- First posted
- 2013-07-24
- Last updated
- 2013-11-28
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT01906918. Inclusion in this directory is not an endorsement.