Trials / Completed
CompletedNCT01903655
Study of the Telomere-telomerase System and the Expression of Candidate Genes in the Leukocytes of Patients With Depressive Disorder: Search for Peripheral Markers of Somatic Stress
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- Sponsor
- Centre Hospitalier Universitaire Dijon · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The mechanisms of oxidative stress and inflammation involved in mood disorders are factors of chronicity and severity. These mechanisms induce a phenomenon of accelerated cellular senescence and are reflected by alterations in systemic gene expression detectable in leukocytes in peripheral blood. The genetic markers of these mechanisms are clinically significant markers. The identification of new genetic markers will make it possible to improve evaluations of the severity and somatic consequences of depressive syndromes.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | telomere length |
Timeline
- Start date
- 2010-04-01
- Primary completion
- 2012-11-01
- Completion
- 2012-11-01
- First posted
- 2013-07-19
- Last updated
- 2026-02-09
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT01903655. Inclusion in this directory is not an endorsement.