Trials / Completed
CompletedNCT01898611
Ghrelin Plus Strength Training in Frail Elderly Study
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- University of Pennsylvania · Academic / Other
- Sex
- All
- Age
- 70 Years
- Healthy volunteers
- Not accepted
Summary
Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the brain. The investigators already know that a single dose of Ghrelin improves food intake immediately after the dose in frail older people. In addition, exercise programs have been shown to improve strength and function in older people. In this study, the investigators are trying to find out if a joint intervention of ghrelin and resistance training will improve walking, balance and leg strength in frail elderly people.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ghrelin | Ghrelin |
| DRUG | Placebo | Saline will be used as a placebo |
Timeline
- Start date
- 2013-07-01
- Primary completion
- 2016-08-31
- Completion
- 2016-08-31
- First posted
- 2013-07-12
- Last updated
- 2019-12-11
- Results posted
- 2018-10-11
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01898611. Inclusion in this directory is not an endorsement.