NCT01895179

Comparison of Time-Restricted Feeding Versus Grazing

Time-Restricted Feeding to Improve Glucose Tolerance and Vascular Condition

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: Male
• Age: 35 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this pilot study is to find out what eating meals in a short time period early in the day (time-restricted feeding) versus eating meals spread out during the day (grazing) does to the body's ability to control blood sugar and to the health of its blood vessels. The investigators hypothesize that time-restricted feeding will be more effective at improving glucose tolerance and vascular condition (inflammation and micro- and macro-vascular function) than grazing.

Detailed description

Each participant will eat according to one of the two eating schedules (grazing or time-restricted feeding) for 5 weeks, have a 7-week washout period, and then eat according to the other eating schedule for 5 weeks. Measurements of glucose homeostasis and vascular condition will be performed before and after a participant follows each eating schedule.

Conditions

• Prediabetes
• Insulin Resistance
• Vascular Diseases

Interventions

Type	Name	Description
OTHER	Time-Restricted Feeding	Time-restricted feeding is a variant of intermittent fasting that involves eating all of one's calories within a few hours each day (typically 4-9 hours), followed by a daily fast of 15-20 hours.
OTHER	Grazing	Grazing involves eating meals spread out over the course of the day.

Timeline

• Start date: 2013-07-01
• Primary completion: 2017-11-01
• Completion: 2017-11-01
• First posted: 2013-07-10
• Last updated: 2018-03-16

Locations

1 site across 1 country: United States