NCT01890616

Constipation and Gut Transit in DMD Patients

Constipation and Gut Transit in Duchenne Muscular Dystrophy Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 8 (actual)
• Sponsor: Children's Hospital Medical Center, Cincinnati · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this research study the investigators want to screen Duchenne Muscular Dystrophy (DMD) patients for signs and symptoms of constipation in patients over 18. The investigators hypothesized: * DMD patients have a high prevalence of constipation than in the general population. * Prevalence of constipation will increase with age and with worsening functional status.

Detailed description

The following procedures will take place during the study. Constipation Assessment: * The patient will be asked to complete a questionnaire about any symptoms of constipation. * A physician from the study team will perform an abdominal physical exam * The patient will have routine x-rays that monitor for spine compression fractures. These films will also be used to assess stool content. Clinical Information The following information will also be collected during the clinic visit ; * Age at diagnosis and genetic mutation * Age at loss of ambulation if applicable * Medications * Functional status

Conditions

• Constipation
• DMD

Interventions

Type	Name	Description
DEVICE	SmartPill ingestion	The participant would ingest the SmartPill and wear the data receiver for up to 5 days.

Timeline

• Start date: 2013-05-01
• Primary completion: 2015-07-01
• Completion: 2015-07-01
• First posted: 2013-07-02
• Last updated: 2020-09-16

Locations

1 site across 1 country: United States