NCT01879384

Monitoring of Bone Free Flaps With Microdialysis

Feasibility of Monitoring of Bone Free Flaps With Microdialysis Catheter Directly Positioned in Bone Tissue

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Microdialysis is admitted to be reliable by numerous surgeons to monitor flaps. Nevertheless, a few authors reported follow up with microdialysis in bone flaps, and they all described the position of the catheter in the surrounding soft tissue muscle. This surrounding soft tissue is not always the reflect of bone vascularisation. The aim is to study the feasibility of a follow up of microanastomosed bone flaps with microdialysis. To reach this goal, investigators perform a clinical prospective research project untitled MTM project

Detailed description

In addition to our classical clinical monitoring, bone microanastomosed flaps for reconstructive facial surgery will be monitored with CMA 70 catheter directly positioned in bone tissue. The monitoring is recorded during 5 days. Glucose, lactate , pyruvate , glycerol rates will be analysed : * every hour at day 1, * every two hours at day 2, * every three hours at day 3,4 and 5. Data are managed with Labpilot software.

Conditions

• Microsurgery
• Head and Neck Reconstructive Surgery
• Head and Neck Cancer
• Head and/or Neck Shotgun Trauma
• Bone Free Flap

Interventions

Type	Name	Description
DEVICE	CMA 70 catheter directly positioned in bone tissue	At the end of the surgery the CMA microdialysis catheter is placed inside the bone

Timeline

• Start date: 2011-02-01
• Primary completion: 2013-05-01
• Completion: 2013-06-01
• First posted: 2013-06-17
• Last updated: 2025-09-19

Locations

1 site across 1 country: France