NCT01879059

The Effects of Altering Physical Activity on Cardiometabolic Health

The Effects of Altering Physical Activity on Endothelial Function, Glycemic Control, and the Blood Flow Response to an Oral Glucose Tolerance Test.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: All
• Age: 19 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The effects of physical inactivity on variations in blood glucose and vascular health are not fully understood. The purpose of this study is to determine if an acute transition from physical activity to inactivity alters vascular health. Specifically, the investigators wish to examine in healthy, lean physically active individuals (obtaining greater than 10,000 steps/day) if decreasing physical activity (obtaining less than 5,000 steps/day) will alter blood flow following a meal a marker of vascular health. Furthermore, the investigators wish to examine if a one day return to physical activity (obtaining \>10,000 steps/day) can restore the detrimental effects on blood flow following a meal.

Detailed description

Herein, we tested the hypothesis that an acute reduction in daily activity (from \>10,000 to \<5,000 steps/day) for 5 days in healthy individuals reduced meal-stimulated blood flow and if a 1 day return to activity improved this outcomes.

Conditions

• Insulin Resistance

Interventions

Type	Name	Description
BEHAVIORAL	Exercise	short period of inactivity (5 days) followed by a return to physical activity (1 day)

Timeline

• Start date: 2012-03-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2013-06-17
• Last updated: 2016-02-08
• Results posted: 2016-02-08

Locations

1 site across 1 country: United States