NCT01876524

tRNS in Anterior Cingulate Cortex Reduces Craving Over Dual Pathology Patients

Transcranial Random Noise Stimulation in Anterior Cingulate Cortex Reduces Craving Over Dual Pathology Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 225 (actual)
• Sponsor: Spanish Foundation for Neurometrics Development · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to study the efficacy and security of noninvasive brain stimulation as a new approach for patients with Substance Use Disorders (SUDs) plus other psychiatric conditions like ADHD, Schizophrenia, Bipolar disorder, etc.

Detailed description

Background: There is an intimate relationship between addictive behaviors and other mental disorders, proven by clinical practice and many epidemiological studies, genetic and neuroscience. This gives risk to the diagnosis of Dual Pathology: an addiction and another mental disorder. Functional neuroimaging studies have shown that anterior cingulate cortex is associated with substance´s dependence and craving. Transcranial random noise stimulation (tRNS) stimulates parts of the brain and can change it´s activity. Researchers are interested in reduce cravings for substance dependence on patients with Dual Pathology using tRNS in anterior cingulate cortex. Aims: To determine whether tRNS in anterior cingulate cortex can reduce craving over Dual Pathology patients.

Conditions

• Substance Use Disorder
• Attention Deficit Disorder With Hyperactivity
• Bipolar Disorder
• Schizophrenia
• Personality Disorder

Interventions

Type	Name	Description
DEVICE	Transcranial Random Noise Stimulation	Random Noise Stimulation between 100 and 500 Hz and 400-500 microAmperes are applied over head in particular areas

Timeline

• Start date: 2013-07-01
• Primary completion: 2014-08-01
• Completion: 2014-09-01
• First posted: 2013-06-12
• Last updated: 2026-02-03

Locations

1 site across 1 country: Spain